Liver cancer has “the first signal”

　　Case 1: Mr. Luo, discovery hepatitis B 12 years. in August, 2006, the physical examination discovered that armor embryo protein (AFP) elevates, for normal value 5 times, supersonic and strengthens the CT inspection in the local hospital line, has not discovered the liver neoplasm. 1 month later, AFP climbs to the normal value 11 times, the line of CT inspection, still the discovery had not been once more unusual. 3 months later, AFP further elevated to normal value 27 times, the CT inspection still demonstrated normally. The multiple CT inspection has not found the problem, let the patient relax vigilantly. 6 months from now on, AFP will elevate normal value 45 times, to the CT inspection, discovers the left liver's cancer stove already as long as the diameter 3.2 centimeters sizes.

　　Case 2: Ms. Tang, is also a hepatitis B patient, every 3~6 month regular physical examination. In May discovered that AFP advances suddenly, to normal value 20 multiple, the line strengthens the CT inspection, has not discovered the liver neoplasm. Goes to another hospital inspection, reexamines AFP and strengthens CT, AFP with the first hospital consistency, strengthens CT not to see the liver unusual infection. Then comes my courtyard seeing a doctor, the hepatic artery angiography to add the iodine oil dye test to demonstrate that liver right leaf near gallbladder place has a diameter is 0. 9 centimeter liver cancer stoves. Ms. Tang from discovered that AFP elevates to accepts the effective treatment, has used less than 2 week-long time.

　　Although the above two liver disease friend was compares the early time at liver cancer to obtain the explicit diagnosis, but compared them to obtain the diagnosis the process, actually let the human have the different feeling. Mr. Luo in discovered that AF P elevates, when is elevates gradually, only satisfies hospital multiple CT the discovery obviously exceptionally, but not to other hospital reexamination, or a consideration line of other keener inspection, caused liver cancer long only then to discover to certain size, has missed the best diagnosis and the treatment opportunity. Comparatively speaking, Ms. Tang is luckier, discovered that AFP elevates namely chases after and never give up, was smaller than the diameter 1 centimeter liver cancer has seized, to obtain the good forward curative effect and use micro creates the treatment to lay the foundation.

　　AFP is may one kind of glycoprotein which examines in the normal person blood serum, the level be very low. The chronic liver disease (elevates in the active stage take transaminase undulatory property as main feature), part of liver cells have the denaturation and necrosis, organism to repair necrosis's liver cell, needs to start the liver cell regeneration mechanism. When the liver cell regeneration is quite active, may have mild elevation, generally does not surpass 100ng/L, and the fluctuation and liver disease's extension turns over to closely related. The pregnancy woman and the gonad embryo tumor patient also has obvious elevation.

　　When has liver cancer, because liver cancer cell has AFP ability, in blood AFP common and carries on obviously elevation, therefore, in the blood AFP elevates may take the diagnosis liver cancer's important basis. What is worth mentioning, is not all liver cancers produces AFP, can have the AFP liver cancer to approximately compose 70%, and has the AFP ability to be different, the approximately 10% liver cancers only produce low level (30~100ng/ml) AFP. Generally speaking, AFP elevates scope and cancer stove size and condition sooner or later not obvious relations. When suspects liver cancer highly by other clues, AFP normal or the level is low cannot take the elimination liver cancer's reason. Hepatitis B and so on chronic liver disease patient is liver cancer good sends the crowd, should periodic inspection AFP, supersonic even strengthen CT, has the development early time by the time at liver cancer to be clear about the diagnosis. AFP elevates is the liver cancer's first signal frequently.

　　Discovers when AFP elevates, should better be chooses another hospital to carry on the reexamination, removes situations and so on verify error. When the AFP density carries on the nature to elevate, when specially climbs to the high level, basic may remove the liver cell regeneration which the liver function fluctuation causes actively and so on factors, should suspect liver cancer highly, needs the line to further inspect. Has the development initial period at liver cancer, because the cancer stove is small, reasons and so on position concealment, the convention supersonic not necessarily can discover with the CT inspection, cannot therefore relax vigilantly, ought to do the angiography and the iodine oil dye test and so on further inspects.

　　AFP except can help the diagnosis liver cancer, but is also helpful to the appraisal treatment result. Before the treatment, AFP high patient, after the treatment, like can reduce gradually for the normal level, prompts liver cancer's treatment is completely and thorough; If reduces after certain level no longer continues to reduce, either starts to elevate, then prompts liver cancer to have highly remains, either has liver cancer stove which other not yet discovered that needs to further inspect and to treat. If after treating, AFP reduces to the normal level, after period of time, gradually elevates, then prompt liver cancer has the recrudescence or sends again, should diagnose positively and treat. What needs to further explain, even if were liver cancer obtained the thorough elimination, after the treatment, AFP not reduce to normally, the rule usually will be very quickly each week drops 50%, until dropped to normally.

　　In brief, AFP elevates is frequently liver cancer has the development first signal, also appraises the treatment result keenest target, liver cancer recrudescence or sends “the barometer” again. Liver cancer patient who elevates obviously regarding AFP says, this early warning signal is unfortunate lucky. Holds it, do not relax!